Humanization and Characterization of an Anti-Ricin Neutralization Monoclonal Antibody
نویسندگان
چکیده
منابع مشابه
Humanization and Characterization of an Anti-Ricin Neutralization Monoclonal Antibody
Ricin is regarded as a high terrorist risk for the public due to its high toxicity and ease of production. Currently, there is no therapeutic or vaccine available against ricin. D9, a murine monoclonal antibody developed previously in our laboratory, can strongly neutralize ricin and is therefore a good candidate for humanization. Humanization of D9 variable regions was achieved by a complement...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2012
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0045595